Inflammasomes are multiprotein platforms for caspase-1 activation which develop in response to a variety of outside and endogenous danger signals, resulting in the production of pro-inflammatory cytokines and the stimulation of inflammatory cell death via caspase-1 activation (4579701).
Formation, Composition & dynamics (Assembly and disassembly)
Relation to human diseases
Proteome
References
Tsuchiya K, Hara H. The inflammasome and its regulation. Crit Rev Immunol. 2014;34(1):41-80. doi: 10.1615/critrevimmunol.2013008686. PMID: 24579701.